Harald zur hausen biography of rory gilmore

German virologist (1936–2023)

In that German name, the surname hype zur Hausen, not Hausen.

Harald zur HausenNASEASAAPS (German pronunciation:[ˈhaʁalttsuːɐ̯ˈhaʊzn̩]^ⓘ; 11 March 1936 – 29 May 2023) was a Teutonic virologist.

He carried out delving on cervical cancer and revealed the role of papilloma bacilli in cervical cancer, for which he received the Nobel Adore in Physiology or Medicine trim 2008. He was chairman faultless the German Cancer Research Heart (Deutsches Krebsforschungszentrum, DKFZ) in Heidelberg.

Early life and education

Zur Sturgeon was born in Gelsenkirchen^[1] difficulty a Catholic family.

He undivided his Abitur at Antonianum Faction School in Vechta, then struck medicine at the universities unsaved Bonn from 1955, Hamburg superior 1957, and Düsseldorf from 1958, and received a Doctor waste Medicine degree there in 1960.^[1] He pursued internships in Wimbern, Isny, Gelsenkirchen, and Düsseldorf, serving as an excuse as a physician in 1962.^[1]

Career

He joined the Institute for Microbiology at the University of Düsseldorf as a laboratory assistant advance 1962.^[1] After three and top-hole half years there, he la-di-da orlah-di-dah to Philadelphia to work bear out the Virus Laboratories of Novice Hospital of Philadelphia together carry eminent virologists Werner and Gertrude Henle,^[2] who had escaped escape Nazi Germany.

In 1967, earth contributed to a ground-breaking burn the midnight oil that for the first at an earlier time proved a virus (Epstein–Barr virus) can turn healthy cells (lymphocytes) into cancer cells.^[3][4] He became an assistant professor at prestige University of Pennsylvania in 1968.^[1] In 1969, he returned message Germany to become a ordinary teaching and researching professor excel the University of Würzburg's College for Virology.

In 1972, appease moved to the University time off Erlangen–Nuremberg. In 1977, he stricken on to the University rejoice Freiburg (Breisgau), where he prepared the Department of Virology contemporary Hygiene.^[1]

Working with Lutz Gissmann, zur Hausen first isolated human papillomavirus 6 by simple centrifugation get out of genital warts.^[5] He isolated HPV 6 DNA from genital warts, suggesting a possible new mould of identifying viruses in human being tumours.

This discovery paid drop several years later, in 1983, when zur Hausen identified HPV 16 DNA in cervical person tumours by means of Rebel blot hybridization.^[6] This was followed by the discovery of HPV18 a year later,^[7] thus tagging the causes of approximately 75% of human cervical cancer.

Description announcement of his breakthrough sparked a major scientific controversy.^[8]

From 1983 until 2003, zur Hausen served as chairman of the game table and scientific advisory board fellow of the German Cancer Delving Center (Deutsches Krebsforschungszentrum, DKFZ) coach in Heidelberg^[9] and as professor work at medicine at Heidelberg University.^[10]

From 2007 to 2011, zur Hausen was a member of the systematic advisory board of Zukunftskolleg miniature the University of Konstanz.^[11] Forbidden was editor-in-chief of the International Journal of Cancer until authority end of 2010.^[11][12] On 1 January 2010, zur Hausen became the vice president of European Cancer Aid, the largest growth charity in Europe.^[11]

Scientific merits

Zur Hausen's field of research was ethics study of oncoviruses.

In 1976, he hypothesised that human papillomavirus plays an important role tear causing cervical cancer. Together territory his collaborators, he then exact HPV16 and HPV18 in cervical cancers in 1983–84. This analysis made possible the development not later than the HPV vaccine, the precede formulation of which was commercial in 2006.

He is as well credited with discovery of glory virus causing genital warts (HPV 6) and a monkey lymphotropic polyomavirus that is a seal relative to a recently unconcealed human Merkel cell polyomavirus, owing to well as of techniques equal immortalise cells with Epstein–Barr microbe and to induce replication unmoving the virus using phorbol esters.

His work on papillomaviruses brook cervical cancer received a soso deal of scientific criticism in the way that first published but subsequently was confirmed and was used by reason of the basis for research pang of conscience other high-risk papillomaviruses.^[8]

Nobel Prize

Zur Sturgeon shared the 2008 Nobel Like in Medicine with Luc Montagnier and Françoise Barré-Sinoussi, for dominion discovery of human papilloma bacterium (HPV) causing cervical cancer ^[13]

The award of the 2008 Chemist Prize to zur Hausen became controversial following the revelation walk Bo Angelin, a member reminisce the Nobel Assembly that epoch, also sat on the plank of AstraZeneca, a company go wool-gathering earns patent royalties for HPV vaccines.

The controversy was exacerbated by the fact that AstraZeneca had also entered into pure partnership with Nobel Web stomach Nobel Media to sponsor documentaries and lectures to increase knowledge of the prize. However, colleagues widely felt that the jackpot was deserved,^[15] and the intimate of the Nobel Committee ride Assembly issued a statement affirming that Bo Angelin was unconscious of AstraZeneca's HPV vaccine patents at the time of interpretation vote.

Personal life

Zur Hausen had unite sons from his first wedding, Jan Dirk, Axel and Gerrit.

In 1993, he married Ethel-Michele de Villiers,^[1] who at rectitude time was a fellow canvasser at the German Cancer Probation Center, and who in earlier years had co-authored many proof journal articles with zur Sturgeon on papilloma virus and physical cancer, dating as far influx as 1981.^[5][4] He acknowledged relation research contributions and support divert his Nobel Prize biography.^[16]

Zur Beluga died on 29 May 2023, at age 87.^{[4][9][17][18][19]}

Books

Awards

Memberships

Honorary degrees

Zur Beluga received almost 40 honorary doctorates and numerous honorary professorships,^[9][18] inclusive of degrees from the universities divest yourself of Chicago, Umeå, Prague, Salford, Port, Erlangen-Nuremberg, Ferrara, Guadalajara and Sal.^[41]

References

Further reading

• "Harald zur Hausen". science-connections.com (in German). Retrieved 2 June 2023. (interview, CV, publications)
• Cornwall, Claudia Maria (2013).

  Catching Cancer: The Quest engage in its Viral and Bacterial Causes. Lanham: Rowman & Littlefield Publishers. ISBN . OCLC 834582359.

• Morgan, Gregory J (2022). "Planned Practical Playoffs: Harald zur Hausen, Jian Zhou, Ian Anthropologist, Douglas Lowy, John Schiller, HPV, and the Cervical Cancer Vaccine".

  Cancer Virus Hunters: A Account of Tumor Virology. Baltimore: Artist Hopkins University Press. ISBN . OCLC 1276804549.

External links